There are no permanent enemies or friends in international relations, only national interests are permanent or supreme. Historically, Pakistan's relations with USSR have never been friendly. The paper will examine the reasons behind the disaffection relationships between Russia and Pakistan. From the USSR's point of view, Pakistan has a strategic relationship with the U.S. and was declared the enemy of Moscow. From Pakistan's point of view, USSR is inclined towards India. In this emerging multipolar world, Pakistan needs to modify its foreign policy according to the changing regional and international environment. Russia, an emerging global power, is reconsidering its policy towards South Asia. Pakistan is a strategically important state in the region. Hence, it is essential for Islamabad to look towards a friendly relationship with regional players, which must be based on mutual trust and cooperation. This qualitative research aims to analyze the international regional and domestic factors responsible for the change in Russian foreign policy and its implication for Pakistan.